We’re both doing well with a largely wheat-free diet. peace, mjh
Better than any NSAID | Wheat Belly Blog
Modern wheat is the perfect inflammation-provoking food. It inflames joints, skin, airways, sinuses, ileum, pancreas, arteries, even brain. And it does so via several means:
1) Gliadin–Due to gliadin’s unique capacity to “unlock” the normal intestinal barriers to foreign substances, numerous foreign polypeptides and other molecules gain access to your bloodstream, some of which are intrinsically inflammatory, while others trigger autoimmunity (causing the body’s immune system to attack its own organs).
2) Wheat germ agglutinin–The abnormal bowel permeability caused by wheat gliadin is amplified by the direct intestinal toxicity of wheat germ agglutinin. This allows wheat germ agglutinin itself to enter the bloodstream, where it is highly toxic (fatal in microgram quantities if injected directly).
3) Amylopectin A–The high glycemic (blood glucose) potential and, even worse, its insulinotrophic (insulin-provoking) effect result in growth of visceral abdominal fat, the sort of fat that is inflammatory, emitting inflammation-mediating proteins into the bloodstream and thereby amplifying inflammation in other parts of the body.
4) Disruptions of bowel flora–All three above wheat components disrupt bowel flora which, in turn, cultivates inflammatory responses in the intestine that are “exported” to the rest of the body. These data are still preliminary, but promise to be among the most exciting insights into how bowel flora impacts health. Disturbed bowel flora may be intrinsically unhealthy, but their metabolites that gain access to the bloodstream introduce another layer of unhealthy effects.
Believe it or not, there are even more ways wheat provokes inflammation. The means by which, for example, wheat gliadin (“gluten”) causes destruction of cerebral tissue resulting in the dementia of “gluten encephalopathy” likely involves several other brain-inflaming pathways.
Better than any NSAID | Wheat Belly Blog
This is the short version of some of the information in Wheat Belly by Dr Davis.